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HYDRO-B18®

Water-soluble form of 18-beta-glycyrrhetinic acid


INCI

AQUA, POLYGLYCERYL-6 CAPRYLATE, GLYCYRRHETINIC ACID, PROLINE

DESCRIPTION

Natural 18-ß-glycyrrhetinic delivered in polyglycerol medium.
HYDRO-B18® is a cutting-edge water-soluble form of natural 18-ß-glycyrrhetinic acid which - in its original form - has poor bioavailability and very low water solubility. 18-ß-glycyrrhetinic acid is regarded as one of the most effective functional ingredients in nature with marked anti-inflammatory and soothing activity. It finds extensive use in the pharmaceutical sector and is often used in its derived salified version.
HYDRO-B18® contains 10% of free and intact 18-ß-glycyrrhetinic acid delivered in a 100% plant-derived medium.

ORIGIN

Natural 18-ß-glycyrrhetinic delivered in polyglycerol medium.

PROPERTIES

  • Transparent soluble in demineralized water at pH 7-9. The presence of surfactant allows widening its transparent solubility in a wider pH range.
  • 100% plant-derived and palm-free.
  • CORTISONE-LIKE INGREDIENT: cortisone-like ingredients such as glycyrrhetinic acid, relieves skin irritations without the typical side effects of corticosteroids. It can be applied daily as part of a preventive skincare regime for sensitive skin and especially in skincare products for infants who have not yet developed a protective hydro-lipid film or acid mantle.
  • ANTI-ITCHING ACTION: Glycyrrhetinic acid reduces the rise of the itching. In particular, it has been shown the role of glycyrrhetinic acid in reducing chronic pruritus by reducing the level of leukotrienes produced.
  • ANTI-MELANOGENIC ACTION: In vitro studies on cell lines have shown that treatment with glycyrrhizin and its aglycone, glycyrrhetinic acid — both before and during sun exposure — prevents oxidative damage.

APPLICATIONS

  • Sensitive skins, After-sun and Shooting transparent water-based applications.
  • Ideal to be incorporated in natural and biodegradable OW and WO emulsions.
% OF USE: 1.0%

TEST

In-vivo tests demonstrate soothing activity:
  • 16% TEWL - after 2 applications of a cream containing 1% HYDRO-B18® on SDS-induced erythema
  • 21% erythema index after 3 applications of a cream containing 1% HYDRO-B18® on SDS-induced erythema
  • In-vivo comparative tests show that HYDRO-B18® is more effective in treating erythema than standard Bisabolol and Ammonium Glycyrrhizate.
>> Cutaneous skin compatibility
>> Soothing efficacy
Watch video >> Soothing efficacy HYDRO-B18®

CHARACTERISTICS

APPEARANCECLEAR LIQUID
COLOURLIGHT YELLOW
ODOURCHARACTERISTIC
PH7.5 – 9.5
DRY RESIDUE (105°C)55 ÷ 57 %
SPECIFIC GRAVITY (25°C)1.13 ÷ 1.15 G/ML
SOLUBILITYTRANSPARENT SOLUBLE IN DEMINERALIZED WATER AT PH 7-9. THE PRESENCE OF SURFACTANT ALLOWS TO WIDEN ITS TRANSPARENT SOLUBILITY IN A WIDER PH RANGE.

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