FUCOREVERSE®

Upcycled seaweed extract
for well-ageing

INCI
Glycerin, Aqua, Hydrolyzed fucoidan

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Fucoreverse is a unique blend of low molecular weight fucoidans, derived from the cell walls of Laminaria seaweed, an upcycled extract from the Iroise Marine Natural Park in Brittany, France. The process involves hydrolyzing fucoidans and concentrating them through purification, resulting in a mixture of sulfated fucose mono, di, and trimers with a molecular weight under 2 kDa.

Designed as a well-ageing ingredient, Fucoreverse supports the skin’s natural defense and repair mechanisms.

EFFICACY TESTS

BIOLOGICAL ACTIVITY

Antioxidant Defenses:

  • Superoxide Dismutase 2 (SOD2): Increases mRNA expression by +457% (p=0.0005), transforming toxic superoxide into less harmful substances.
  • Metallothionein 2A (MT2A): Enhances mRNA expression by +232% (p=0.0008), crucial for combating oxidative stress.

AUTOPHAGY:

  • DNA Damage-Regulated Autophagy Modulator 1 (DRAM1): Boosts mRNA expression by +297% (p=0.012), aiding in stress-induced autophagy and cell survival.

Detoxification:

  • Metallothionein 1G (MT1G): Amplifies mRNA expression by +1010% (p=0.0013), supporting detoxification.
  • Lactoylglutathione Lyase (GLO1): Increases mRNA expression by +139% (p=0.011), crucial for detoxifying harmful compounds.

EXTRACELLULAR MATRIX REGENERATION

  • Dermatopontin protein primary function is a structural component of the Extracellular matrix, cell adhesion, modulation TGF-beta. + 1492 % Dermatopotin mRNA expression (p= 0.0003) Exostosin-like 2 controls heparin sulfate biosynthesis. + 132 % Exostosin-like 2 mRNA expression (p= 0.01).
  • Fucoreverse stimulates the fibroblasts proliferations.
  • Fucoreverse significantly stimulates type 1 collagen synthesis.

ANTI WRINKLES EFFICACY

  • Average wrinkle depth reduction of 6.3%, with 70% of participants to the test noticing visible improvements and some seeing reductions up to 18.9%. Additionally, significant reduction in skin irritation compared to the placebo group.

    (Clinical study details: The study involved 42 women aged 43-68 with crow’s feet wrinkles. Participants applied a cream with 1.5% Fucoreverse or a placebo twice daily for 28 days. Wrinkle depth was assessed using skin profilometry on Day 0 and Day 28.)

 

Key Product Details

% OF USE

1.5%

 

APPLICATIONS

Well-ageing treatments, Anti-wrinkle creams, Skin perfectors,
Soothing formulations, Sensitive skin care,
After-sun care, Eye contour products

TECHNICAL DATA
APPEARANCE LIMPID LIQUID
COLOUR YELLOW
SOLUBILITY WATER
ISO 16128 1
PRESERVATIVE NONE
PROPERTIES
  • Reduces Wrinkles: Clinically proven to decrease wrinkle depth by an average of 6.3%, with some reductions up to 18.9%.
  • Soothes Skin Irritation: Effectively reduces skin irritation and provides excellent tolerance, making it ideal for sensitive skin.
  • Boosts Skin Defense: Enhances natural antioxidant defenses and detoxification processes, protecting against UV rays, pollution, and blue light.
  • Stimulates Dermal Repair: Promotes collagen synthesis and fibroblast proliferation, improving skin firmness and elasticity.
  • Sustainable and Natural: Derived from upcycled seaweed extract, ensuring 100% natural origin and eco-friendly production.
  • Versatile Applications: Suitable for anti-aging treatments, anti-wrinkle creams, soothing formulations, and sensitive skin care products.

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